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Performance Chemicals Division

HOBT (1-Hydroxybenzotriazole)

Standard racemization-suppressing coupling additive used extensively in peptide bond formation during solid-phase and solution-phase synthesis.

AvailableCoupling additiveCAS 2592-95-2
✓Fine & Specialty Chemical
✓Peptide synthesis reagent
✓Scalable Manufacturing

Standard racemization-suppressing coupling additive used extensively in peptide bond formation during solid-phase and solution-phase synthesis.

Technical Overview

HOBT (1-Hydroxybenzotriazole) – CAS 2592-95-2

Available

CAS Number

2592-95-2

Category

Coupling additive

Molecular Formula

C6H5N3O

Molecular Weight

135.12

Synonyms

1,2,3-Benzotriazol-1-ol,HOBt (anhydrous)

Description

Standard racemization-suppressing coupling additive used extensively in peptide bond formation during solid-phase and solution-phase synthesis.

Applications

  • Peptide synthesis
  • Coupling additive

Specifications

Appearance
White crystalline solid
Assay
NLT 98.0%
Melting Point
156 - 159 °C (decomposes)

Handling & Supply Details

Storage Conditions

Store in a cool, dry place below 25°C, tightly sealed and protected from moisture; ship and store wetted or as the monohydrate where required by regulation.

Packaging

25 kg fiber drum with inner liner

Shelf Life

12 months

Product Inquiry

Disclaimer

Products offered are intended for industrial, specialty, formulation development, R&D, registration and/or export purposes only. The responsibility for ensuring compliance with local regulations and that the product does not infringe any third-party patent or intellectual property rights rests solely with the buyer.

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