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Contract manufacturing, APIs, injectables, and specialty chemicals background
Contract Manufacturing Division

Contract Manufacturing for APIs, Injectables & Specialty Chemicals

Reliable pharmaceutical and chemical contract manufacturing with global compliance standards, advanced capabilities, and dedicated support from concept to commercial production.

+91 8104 389 961
4 × WHO-GMP facilities3,500+ MT capacity1 kg to commercial scale
1
Manufacturing Facilities
WHO-GMP Certified
1137
+
MT Annual Capacity
Scalable Production
0
+
Reaction Types
Complex Chemistry
0
%
Regulatory Compliance
Global Standards
Trusted manufacturing partner

Why Choose SIGMAK

Leading pharmaceutical and chemical contract manufacturing partner with proven expertise, technical discipline, and global compliance alignment.

4 WHO-GMP
Partner facilities
1 kg to commercial
Scale range
Technical + regulatory
Support model
Manufacturing platform

SIGMAK delivers comprehensive contract manufacturing solutions through our exclusive network of four strategically located WHO-GMP certified partner facilities across India. Our state-of-the-art manufacturing units are equipped to handle over 15 types of complex chemical reactions with a combined installed capacity exceeding 3,500 MT per annum, supporting pharmaceutical and chemical manufacturing requirements from laboratory scale to full commercial production.

Our advanced capabilities extend to cGMP-compliant API development, pharmaceutical intermediates, and specialty chemical manufacturing from small-scale (1-10 kg) to mid-scale production. Our infrastructure is specifically designed to manage complex chemistries, challenging reaction conditions, and specialized synthesis requirements while maintaining the highest quality and regulatory standards.

Core advantages

Proven depth across execution, compliance, and support

Global regulatory compliance and quality standards

Dedicated project management and technical support

Confidentiality and IP protection guaranteed

Scalable production from lab to commercial scale

Manufacturing capabilities

Contract Manufacturing

Advanced chemical manufacturing capabilities for specialty chemicals, intermediates, and custom molecules presented through a cleaner, more premium capability framework.

Industrial and regulated programs

Specialty Chemicals

Reliable execution for specialty intermediates and performance-led chemical programs with commercial scalability built in from the start.

  • Fine chemicals and specialty intermediates
  • Agrochemical intermediates and active ingredients
  • Performance chemicals for industrial applications
Designed around your route

Custom Synthesis

Process development, optimization, and transfer support for customers who need speed, confidentiality, and technical depth.

  • Bespoke chemical synthesis solutions
  • Process optimization and cost reduction
  • Technology transfer and scale-up services
Audit-ready by design

Quality Assurance

Documentation discipline, validated controls, and analytical rigor that support regulated supply expectations across every batch.

  • Comprehensive analytical testing and validation
  • International quality standards compliance
  • Certificate of Analysis (CoA) for every batch
Technical depth

Process Chemistry Expertise

Comprehensive capabilities across diverse chemical transformations, restructured into a sharper and more premium technical presentation.

-100 C to +200 C
Temperature range
Pressure
Seal tube and autoclave
Chiral + catalytic
Advanced route support
01

Core Capabilities

Execution envelope
  • Low & High Temperature Reactions: −100 °C to +200 °C
  • Pressure Reactions: Seal tube, autoclave
  • Hydrogenation: Pd/C, Rh/C, Ra-Ni, Adam's Catalyst
  • Pyrophoric Chemistry: LAH, Super Hydride, NBL, LDA
  • Metal-Mediated Reactions: Grignard, Na, Li, Pd, Cu, etc.
02

Advanced Catalysis

Catalytic platforms
  • Cross-Coupling Reactions: Suzuki, Kumada, Stille, Sonogashira, Heck, Negishi, Buchwald
  • Metathesis Reactions: Grubbs
Chiral chemistry
  • Chiral Synthesis & Resolution
  • Asymmetric Synthesis: Using chiral auxiliaries, enantio- and diastereo-selective methods
  • Chiral Separation
03

Transformation Depth

Heterocyclic synthesis
  • Synthesis & ring formation of pyridine, pyrimidine, indole, indazole, and other nitrogen- and oxygen-containing heterocycles
Functional group transformations
  • Alkylation, Acylation, Amidation, Esterification, Formylation
  • Oxidation, Reduction, Condensation
  • Named Reactions: Friedel-Crafts, Sandmeyer
  • Specialty Syntheses: Boronic Acid Synthesis
Background

Ready to Start Your Project?

Contact us to discuss your manufacturing requirements and how we can help bring your products to market with excellence and precision.

Schedule a Call

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