SIGMAK
Sigmak supplies cosmetic-grade peptides for anti-aging, brightening, hair care, and premium skincare formulations. Each product is supplied with a batch-specific COA and HPLC purity data.
GHK-Cu
CAS 89030-95-5
Copper Tripeptide-1 (GHK-Cu) is a carrier peptide that stimulates collagen synthesis by up to 70%, accelerates wound healing, and supports hair follicle health. HPLC ≥99.85%. COA verified.
Argireline
CAS 616204-22-9
Neurotransmitter inhibitor — a topical Botox alternative that reduces expression lines.
Matrixyl 3000
CAS 147732-56-7 + 221227-05-0
Signal peptide blend — stimulates collagen and elastin while inhibiting IL-6.
Matrixyl Synthe'6
CAS 1447824-23-8
Signal peptide — stimulates 6 matrix proteins including collagen I/III/IV, HA, and fibronectin.
SYN-AKE
CAS 823202-99-9
Snake venom mimic — relaxes facial muscles and smooths expression lines.
Biotinyl Tripeptide-1
CAS 299157-54-3
Hair peptide — anchors the follicle, prevents hair loss, and strengthens the hair shaft.
b-White
CAS 1206525-47-4
Brightening peptide — tyrosinase inhibition reduces melanin and corrects hyperpigmentation.
SNAP-8
CAS 868844-74-0
Enhanced neurotransmitter inhibitor — stronger than Argireline, targeting SNAP-25.
CAS 64963-01-5
Enkephalin-like opioid receptor peptide that inhibits neurotransmitter release, synergistic with Argireline for anti-wrinkle action.
CAS 1400634-44-7
Next-generation expression-line reducer targeting the SNAP-25 protein through a mechanism distinct from Argireline.
CAS 820959-17-9
Reduces eye puffiness and under-eye bags through anti-glycation activity and improved microcirculation.
Matrixyl
CAS 214047-00-4
The original Matrixyl peptide — clinically proven to stimulate collagen I, III, and IV synthesis, reducing wrinkle depth by up to 68%.
CAS 623172-56-5
Biomimetic peptide that stimulates the TGF-β pathway for natural collagen I production and reduces inflammation-driven collagen breakdown.
CAS 72957-36-9
The core GHK tripeptide that signals collagen and elastin production — the foundational anti-aging active.
CAS 170809-51-5
Lipopeptide that stimulates fibroblasts to produce collagen and improve the quality of the collagen network.
CAS 221227-05-0
Anti-inflammatory peptide that reduces IL-6, an inflammatory cytokine linked to collagen breakdown and skin aging.
CAS 928007-64-1
Stimulates lumican, a proteoglycan that organizes collagen fibers, improving collagen fiber quality and skin structure.
Anti-sagging peptide that improves skin elasticity and fights gravity-induced loss of facial contour.
AHK-Cu
CAS 130120-57-9
Hair-focused copper peptide that stimulates hair follicles and supports scalp repair.
CAS 960433-99-2
Inhibits collagen-degrading MMP enzymes and improves collagen fiber structure; prevents and repairs stretch marks.
CAS 158563-45-2
Alpha-MSH receptor antagonist that inhibits melanin synthesis, effective on dark spots and uneven skin tone.
CAS 170809-51-5
Melanin synthesis inhibitor for skin brightening and pigmentation treatment.
CAS 448944-47-6
Self-tanning peptide that stimulates natural melanin production without UV exposure; also supports hair pigmentation.
CAS 24587-36-8
Dual-action peptide that reduces melanin production and improves lymphatic drainage to reduce puffiness and dark circles.
CAS 221227-05-0
Clinically studied to reduce dark circles by targeting haemoglobin degradation products under the eye skin.
Reduces under-eye bags and puffiness by improving capillary resistance and lymphatic drainage.
CAS 827306-88-7
Inhibits DHT-producing 5α-reductase enzyme to prevent hair thinning; clinically shown to increase hair density and supports eyebrow and lash density.
Stimulates melanocyte activity in hair follicles to address premature greying and restore natural hair pigmentation.
Improves scalp microcirculation and strengthens hair follicle anchoring for healthier hair growth.
Multi-function hair peptide supporting hair volume, brightness, and antioxidant protection.
CAS 959610-30-1
Clinically proven to lengthen and thicken eyelashes and fortify the hair shaft for bolder, more defined eyes.
Lip Grade
CAS 147732-56-7
Collagen-stimulating peptide formulated for lip plumping and volume enhancement.
CAS 170809-51-5 + 221227-05-0
Dual-peptide blend combining collagen stimulation with anti-inflammatory action for lip volume, hydration, and anti-aging of the lip border.
CAS 196604-48-9
Calms neurogenic inflammation and strengthens the skin barrier, suited to sensitive skin care.
CAS 161518-69-0
Yeast-derived hexapeptide supporting skin renewal, hydration, and firmness.
CAS 757942-88-2
Thymus-inspired peptide supporting immune defence, wound healing, and skin regeneration.
CAS 960433-99-2
Targets the progerin aging protein to slow cellular aging and restore skin elasticity.
CAS 466691-40-7
Antimicrobial peptide that inhibits P. acnes bacteria to reduce acne without antibiotics.
Antimicrobial
Broad-spectrum antimicrobial peptide with low hemolytic activity for acne, scalp conditions, and infection prevention.
Body-sculpting peptide that reduces cellulite and firms skin, ideal for body cream formulations.
CAS 5875-06-9
Lifts and firms skin by maintaining collagen fiber integrity — excellent for neck and décolleté serums.
Firming peptide for breast and body contouring formulations, improving skin elasticity and tone.
CAS 305-84-0
Natural dipeptide with powerful anti-glycation and antioxidant action to help prevent skin aging.
GSH
CAS 70-18-8
The skin's master antioxidant — brightens, detoxifies, and protects against oxidative stress.
CAS 616204-22-9 + 64963-01-5
Synergistic blend of two neurotransmitter-inhibitor peptides for superior expression-line reduction.
CAS 89030-95-5 + 299157-54-3
Powerful hair peptide combination for hair loss treatment and scalp repair serums.
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