HOBT (1-Hydroxybenzotriazole Monohydrate) • CAS 80029-43-2
Fine Chemical • Available • Coupling additive
HOBT (1-Hydroxybenzotriazole Monohydrate) – CAS 80029-43-2
1-Hydroxy-1H-benzotriazole monohydrate
Product Code
PPC017
CAS Number
80029-43-2
Category
Coupling additive
Molecular Formula
C6H5N3O · H2O
Molecular Weight
153.14
Chemical Class
Peptide coupling reagent
Synonyms
1,2,3-Benzotriazol-1-ol monohydrate,HOBt·H2O
Description
High-purity HOBT Monohydrate (1-Hydroxybenzotriazole Monohydrate, CAS 80029-43-2) supplied as a white to almost white crystalline powder. The stabilized monohydrate form of the widely used racemization-suppressing coupling additive for amide and peptide bond formation, safer to handle and transport than the anhydrous form.
Applications
- Racemization-suppressing additive in carbodiimide-mediated amide coupling
- Peptide synthesis reagent
- Pharmaceutical API synthesis
Specifications
Appearance
White to almost white crystalline powder
Assay
NLT 98.0%
Melting Point
156 - 159 °C (decomposes)
Handling & Supply Details
Storage Conditions
Store in a cool, dry place below 25°C, tightly sealed and protected from moisture.
Packaging
25 kg fiber drum with inner liner
Shelf Life
12 months