2-Acetylthiophene • CAS 88-15-3
Fine Chemical • Available • Thiophene derivative
2-Acetylthiophene – CAS 88-15-3
1-(Thiophen-2-yl)ethan-1-one
CAS Number
88-15-3
Category
Thiophene derivative
Molecular Formula
C6H6OS
Molecular Weight
126.17
Chemical Class
Pharmaceutical & fragrance intermediate
Synonyms
Thiophene-2-Acetyl,2-Thienyl Methyl Ketone,Methyl 2-Thienyl Ketone,2-Acetothienone,Methyl Thienyl Ketone
Description
High-purity 2-Acetylthiophene (CAS 88-15-3), GC assay 99.99%, supplied as a clear to slight yellowish liquid. A key thiophene-based building block used in pharmaceutical synthesis and flavor & fragrance manufacturing, backed by a Certificate of Analysis confirming compliance across appearance, moisture, density, colour, assay, and impurity parameters.
Applications
- Pharmaceutical intermediate for thiophene-based active pharmaceutical ingredient synthesis
- Flavor and fragrance industry for its characteristic roasted, nutty, coffee-like aroma profile
- Building block for agrochemical and specialty organic synthesis
- Heterocyclic chemistry research and custom synthesis applications
Specifications
Appearance
Clear liquid, pale yellow to yellow
Identification
FTIR chromatogram is concordant with that of certified reference standard
Odor
Sweet, nutty, popcorn hazelnut-like
Boiling Point
213 °C to 214 °C at 760 mmHg
Specific Gravity at 25 °C
1.168
Refractive Index at 20 °C
1.565 - 1.575
Solubility
Immiscible or only slightly soluble in water; miscible and highly soluble in common organic solvents such as methanol, ethanol, ether, and benzene
Moisture Content by KF (%)
Max. 0.50
Density at Ambient (gm/ml)
1.140 - 1.180
Colour (Gardner Scale)
Max. 3 Units
Assay (Area %) by GC
Min. 99.0
3-Acetyl Thiophene (Area %)
Max. 0.25
Total Impurities (Area %)
Max. 1.0
Handling & Supply Details
Packaging
200 kg steel drum; 1000 kg IBC
Shelf Life
18 months (retest period)