
Contract Manufacturing for APIs, Injectables & Specialty Chemicals
Reliable pharmaceutical and chemical contract manufacturing with global compliance standards, advanced capabilities, and dedicated support from concept to commercial production.
Why Choose SIGMAK
Leading pharmaceutical and chemical contract manufacturing partner with proven expertise, technical discipline, and global compliance alignment.
SIGMAK delivers comprehensive contract manufacturing solutions through our exclusive network of four strategically located WHO-GMP certified partner facilities across India. Our state-of-the-art manufacturing units are equipped to handle over 15 types of complex chemical reactions with a combined installed capacity exceeding 3,500 MT per annum, supporting pharmaceutical and chemical manufacturing requirements from laboratory scale to full commercial production.
Our advanced capabilities extend to cGMP-compliant API development, pharmaceutical intermediates, and specialty chemical manufacturing from small-scale (1-10 kg) to mid-scale production. Our infrastructure is specifically designed to manage complex chemistries, challenging reaction conditions, and specialized synthesis requirements while maintaining the highest quality and regulatory standards.
Proven depth across execution, compliance, and support
Global regulatory compliance and quality standards
Dedicated project management and technical support
Confidentiality and IP protection guaranteed
Scalable production from lab to commercial scale
Contract Manufacturing
Advanced chemical manufacturing capabilities for specialty chemicals, intermediates, and custom molecules presented through a cleaner, more premium capability framework.
Specialty Chemicals
Reliable execution for specialty intermediates and performance-led chemical programs with commercial scalability built in from the start.
- Fine chemicals and specialty intermediates
- Agrochemical intermediates and active ingredients
- Performance chemicals for industrial applications
Custom Synthesis
Process development, optimization, and transfer support for customers who need speed, confidentiality, and technical depth.
- Bespoke chemical synthesis solutions
- Process optimization and cost reduction
- Technology transfer and scale-up services
Quality Assurance
Documentation discipline, validated controls, and analytical rigor that support regulated supply expectations across every batch.
- Comprehensive analytical testing and validation
- International quality standards compliance
- Certificate of Analysis (CoA) for every batch
Process Chemistry Expertise
Comprehensive capabilities across diverse chemical transformations, restructured into a sharper and more premium technical presentation.
Core Capabilities
- Low & High Temperature Reactions: −100 °C to +200 °C
- Pressure Reactions: Seal tube, autoclave
- Hydrogenation: Pd/C, Rh/C, Ra-Ni, Adam's Catalyst
- Pyrophoric Chemistry: LAH, Super Hydride, NBL, LDA
- Metal-Mediated Reactions: Grignard, Na, Li, Pd, Cu, etc.
Advanced Catalysis
- Cross-Coupling Reactions: Suzuki, Kumada, Stille, Sonogashira, Heck, Negishi, Buchwald
- Metathesis Reactions: Grubbs
- Chiral Synthesis & Resolution
- Asymmetric Synthesis: Using chiral auxiliaries, enantio- and diastereo-selective methods
- Chiral Separation
Transformation Depth
- Synthesis & ring formation of pyridine, pyrimidine, indole, indazole, and other nitrogen- and oxygen-containing heterocycles
- Alkylation, Acylation, Amidation, Esterification, Formylation
- Oxidation, Reduction, Condensation
- Named Reactions: Friedel-Crafts, Sandmeyer
- Specialty Syntheses: Boronic Acid Synthesis

Ready to Start Your Project?
Contact us to discuss your manufacturing requirements and how we can help bring your products to market with excellence and precision.